Peraglow For those who are interested in getting Botox, they should first weigh the pros and cons. With regard to the side effects; they should not worry so much. There are no permanent side effects in this procedure. Once the treatment wears off after an average span of four to six months, the wrinkles gradually return to their former appearance before treatment. Thus it will not worsen the appearance as it was before the treatment. Regarding the minor and temporary side effects, there will be temporary bruising and the patient may suffer from headache within the first two days after injection only. If the doctor commits slip-ups, it may cause temporary drooling for shots administered around the mouth, and drooping eyelids for shots in the eye area, which usually lasts for three weeks and totally removed once the Botox wears off. It is best that clinics who have Botox Houston board certified professionals administer Botox in order to avoid these incidents.